产品分类
Irinotecan
- CAS NO.：97682-44-5
- 品牌名称：LKT Labs
- 品牌货号：I6932-250 mg
- 产品级别：≥98%
- 包装规格：250 mg
- 本店售价：8,558.4810,068.80
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产品介绍
Irinotecan,,货号:I6932-250 mg,品牌:LKT Labs
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Irinotecan is an analog of camptothecin that is used clinically to treat colon and ovarian cancers, among others. Irinotecan exhibits anticancer chemotherapeutic, anti-angiogenic, and immunosuppressive activities. Irinotecan inhibits DNA topoisomerase I and sensitizes tumors to the effects of radiation. In glioma models, irinotecan decreases the number of tumor vessels and decreases expression of VEGF and HIF-1α, inhibiting tumor growth. Irinotecan also moderates inhibition of dendritic cell differentiation and may produce cholinergic side effects, suggesting potential inhibition of acetylcholinesterase (AChE) as well.