产品分类
Neomycin Sulfate
- CAS NO.：1405-10-3
- 品牌名称：LKT Labs
- 品牌货号：N1755-100 g
- 产品级别：≥98%
- 包装规格：100 g
- 本店售价：2,543.202,992.00
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产品介绍
Neomycin Sulfate,,货号:N1755-100 g,品牌:LKT Labs
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Neomycin is a polycationic aminoglycoside antibiotic that exhibits antibacterial and neuromodulatory activities; it was originally found in species of Streptomyces. Neomycin binds to 23S rRNA, constraining tRNA in the P-site, inhibiting translocation and ribosomal recycling; together, this results in inhibition of protein synthesis. Neomycin B binds and inhibits bacterial RNase P and bacterial T box antiterminator RNA. Neomycin B inhibits mammalian RNA splicing as well. Neomycin also noncompetitively inhibits cation channels, including P2X receptors and transient receptor potential vanilloid receptor 1 (TRPV1) channels. Additionally, this compound inhibits Ca2+ influx, preventing presynaptic release of acetylcholine and norepinephrine in feline superior cervical ganglia.