产品分类
Valproic Acid
- 中文名称：丙戊酸
- CAS NO.：[99-66-1]
- 品牌名称：Wako
- 品牌货号：225-01072
- 产品级别：98.0% - 102.0% (Titration)98.0+% (Capillary GC),生物
- 包装规格：25g
- 本店售价：1,450.001,600.00
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产品介绍
Valproic Acid,丙戊酸,货号:225-01072,品牌:Wako
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Antiepileptic. It has an activity enhancing effect on the GABA nerve system.
This product is for research use only. Do not administer it to human.
Cell Biological ResearchFor Research on Cell Cycle and TranscriptionHistone Deacetylase (HDAC) InhibitorsHistone deacetylase (HDAC) plays a central role in chromatin structure formation associated with the nuclear distribution of DNA. There are presently 17 known types of this enzyme in mammals, which are classifiedinto 3 classes (see table below). Also, HDAC Class III has been reported to be associated with regulation of aging and life span.
Mammalian HDAC Class I: Localized in the nucleus. Is similar to RPD3 enzyme. [Types : HDAC1-3, 8]
Mammalian HDAC Class II: Localized in the nucleus and cytoplasm and shuttles between the two. Similar to HDA1 enzyme. [Types: HDAC4-7, 9, 10]
Mammalian HDAC Class III: NAD-dependent enzyme. Localized in the nucleus and cytoplasm. Also called Sirtuin and is similar to SIR2 enzyme. [Types : Sirt 1-7]
HDAC inhibitors show connections with cell division cycles and differentiation, as well as with antitumor activity and apoptosis-inducing activity through the inhibition of the deacetylating activity of HDAC. They can be used for studies on cellular functions involving histone deacetylase.