产品介绍
Dacomitinib (PF299804, PF299),,货号:CC2883,品牌:Chemcatch
PF-299804 is a potent, irreversible pan-ErbB inhibitor, mostly to EGFR with IC50 of 6 nM, effective against NSCLCs with EGFR or ERBB2 mutations (resistant to gefitinib) as well as those harboring the EGFR T790M mutation. Phase 2.
Target:EGFR
Pathway:Protein Tyrosine Kinase
MW:469.94