产品介绍
Avagacestat (BMS-708163),,货号:CC1418,品牌:Chemcatch
Avagacestat (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
Target:Gamma-secretase
Pathway:Proteases
MW:520.88