产品介绍
Foretinib (GSK1363089),,货号:CC1267,品牌:Chemcatch
Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met and KDR with IC50 of 0.4 nM and 0.9 nM. Less potent against Ron, Flt-1/3/4, Kit, PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.
Target:c-Met
Pathway:Protein Tyrosine Kinase
MW:632.65