产品介绍
Linifanib (ABT-869),利尼伐尼,货号:CC1159,品牌:Chemcatch
Linifanib (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, Flt-1/3 and PDGFRβ with IC50 of 4 nM, 3 nM, 3 nM/4 nM and 66 nM respectively, mostly effective in mutant kinase-dependent cancer cells (i.e. FLT3). Phase 3.
Target:VEGFR
Pathway:Protein Tyrosine Kinase
MW:375.41